Loxo Oncology - PharmaKB

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Disease Reports

Disease Reports

Company ReportsLoxo Oncology

Loxo Oncology(LOXO)

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Jaypirca	Pirtobrutinib	2023-01-27	2036	Mantle-cell lymphoma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

non-alcoholic fatty liver disease

,

,

alzheimer disease

,

,

hepatic insufficiency

,

chronic renal insufficiency

,

chronic kidney failure

,

cardiovascular diseases

,

coronary disease

,

acute coronary syndrome

,

cardiac catheterization

,

heart valve prosthesis

,

venous thrombosis

,

,

,

replacement arthroplasty knee

,

secondary prevention

,

neoplasm metastasis

,

replacement arthroplasty hip

,

,

,

percutaneous coronary intervention

,

intracranial sinus thrombosis

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

,

renal insufficiency

,

replacement arthroplasty

,

cognitive dysfunction

,

heart valve diseases

,

coronary artery disease

,

myocardial ischemia

,

,

,

cerebral infarction

,

myocardial infarction

,

,

,

,

cognition disorders

,

,

blood coagulation tests

,

drug-related side effects and adverse reactions

,

blood coagulation disorders

,

hemostatic disorders

,

hemorrhagic disorders

,

medication adherence

,

recreational drug use

,

,

transient ischemic attack

Antithrombin iii

ulcerative colitis

,

,

breast neoplasms

,

atopic dermatitis

,

,

,

disease susceptibility

,

healthy volunteers/patients

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

myelodysplastic syndromes

,

,

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

beta-thalassemia

,

healthy volunteers/patients

,

venous thromboembolism

,

thromboembolism

,

atrial fibrillation

,

,

,

cardiovascular diseases

,

ischemic stroke

,

cerebral hemorrhage

,

vascular diseases

pharmacokinetics

,

non-small-cell lung carcinoma

,

chronic urticaria

,

,

waldenstrom macroglobulinemia

,

peripheral nervous system diseases

,

,

,

,

,

peptic ulcer hemorrhage

,

,

allergic rhinitis

,

,

allergic rhinitis perennial

healthy volunteers/patients

,

drug interactions

,

pharmacokinetics

,

medical sociology

,

biological availability

,

hypophosphatemia

,

kidney diseases

,

brain neoplasms

,

neuroendocrine tumors

,

carcinoid tumor

,

pancreatic ductal carcinoma

,

acinar cell carcinoma

,

,

oligodendroglioma

,

,

promyelocytic leukemia acute

,

renal insufficiency

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

invasive hydatidiform mole

,

,

,

myeloid leukemia

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

,

,

ovarian neoplasms

,

,

neoplasm metastasis

,

pancreatic neoplasms

,

gastrointestinal stromal tumors

,

,

kidney neoplasms

,

ovarian epithelial carcinoma

,

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

,

bile duct neoplasms

,

prostatic neoplasms

,

urinary bladder neoplasms

,

esophageal neoplasms

,

squamous cell neoplasms

,

rhabdomyosarcoma

,

non-hodgkin lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

,

mantle-cell lymphoma

,

disease progression

,

myeloproliferative disorders

,

biphenotypic leukemia acute

,

triple negative breast neoplasms

,

stomach neoplasms

,

fallopian tube neoplasms

,

small cell lung carcinoma

,

atopic dermatitis

,

,

,

transitional cell carcinoma

,

urinary bladder diseases

,

uterine cervical neoplasms

,

myelomonocytic leukemia chronic

,

adenocarcinoma of lung

,

plasma cell neoplasms

,

squamous cell carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

,

communicable diseases

,

rectal neoplasms

,

infectious skin diseases

,

,

colonic neoplasms

,

,

blood coagulation disorders

,

hemostatic disorders

,

bacterial infections

,

soft tissue infections

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

renal cell carcinoma

,

wounds and injuries

,

chemical and drug induced liver injury

,

bacterial skin diseases

,

atrial fibrillation

,

meningeal neoplasms

,

meningeal carcinomatosis

,

,

barrett esophagus

,

pancreatic neoplasms

,

prostatic neoplasms

Polyglycolic acid

healthy volunteers/patients

,

pancreatic ductal carcinoma

,

gastrointestinal neoplasms

,

intestinal neoplasms

,

psoriatic arthritis

,

systemic lupus erythematosus

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

philadelphia chromosome

,

lymphoid leukemia

,

head and neck neoplasms

,

,

pancreatic neoplasms

,

colonic neoplasms

,

residual neoplasm

,

biliary tract neoplasms

,

hematologic neoplasms

,

ovarian neoplasms

,

fallopian tube neoplasms

,

renal cell carcinoma

,

urologic neoplasms

,

triple negative breast neoplasms

,

,

transitional cell carcinoma

,

squamous cell neoplasms

,

adenocarcinoma of lung

,

esophageal neoplasms

,

,

polyneuropathies

,

rectal neoplasms

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

,

malignant mesothelioma

,

,

,

stomach neoplasms

,

squamous cell carcinoma of head and neck

,

,

breast neoplasms

,

microsatellite instability

,

squamous cell carcinoma

,

rheumatoid arthritis

,

,

premature birth

,

geriatric assessment

,

hodgkin disease

,

,

pancreatic neoplasms

,

pancreatic ductal carcinoma

,

,

colonic neoplasms

,

rectal neoplasms

,

carotid artery diseases

,

atherosclerosis

,

,

hematologic neoplasms

,

sezary syndrome

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia t-cell

,

t-cell lymphoma

,

prolymphocytic leukemia

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

prolymphocytic leukemia b-cell

,

renal cell carcinoma

,

kidney neoplasms

,

gastrointestinal neoplasms

,

biliary tract neoplasms

,

hypercholesterolemia

,

,

,

hyperlipidemias

,

,

colorectal neoplasms

,

hyperlipoproteinemias

,

esophageal neoplasms

,

postmenopausal osteoporosis

,

hyperlipoproteinemia type v

,

familial combined hyperlipidemia

,

stomach neoplasms

,

non-small-cell lung carcinoma

,

,

,

esophageal squamous cell carcinoma

,

type 2 diabetes mellitus

,

diabetes mellitus

,

vitamin d deficiency

,

non-hodgkin lymphoma

,

,

hyperlipoproteinemia type ii

,

,

,

,

cardiovascular diseases

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

heart transplantation

,

polycystic ovary syndrome

,

,

,

atopic dermatitis

,

,

non-small-cell lung carcinoma

,

healthy volunteers/patients

1

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