Loxo Oncology - PharmaKB

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Disease Reports

Company ReportsLoxo Oncology

Loxo Oncology(LOXO)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Jaypirca	Pirtobrutinib	2023-01-27	2036	Mantle-cell lymphoma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

non-alcoholic fatty liver disease

,

,

alzheimer disease

,

,

hepatic insufficiency

,

chronic renal insufficiency

,

chronic kidney failure

,

cardiovascular diseases

,

coronary disease

,

acute coronary syndrome

,

cardiac catheterization

,

heart valve prosthesis

,

venous thrombosis

,

,

,

replacement arthroplasty knee

,

secondary prevention

,

neoplasm metastasis

,

replacement arthroplasty hip

,

,

,

percutaneous coronary intervention

,

intracranial sinus thrombosis

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

,

renal insufficiency

,

replacement arthroplasty

,

cognitive dysfunction

,

heart valve diseases

,

coronary artery disease

,

myocardial ischemia

,

,

,

cerebral infarction

,

myocardial infarction

,

,

,

,

cognition disorders

,

,

blood coagulation tests

,

drug-related side effects and adverse reactions

,

blood coagulation disorders

,

hemostatic disorders

,

hemorrhagic disorders

,

medication adherence

,

recreational drug use

,

,

transient ischemic attack

pharmacokinetics

,

non-small-cell lung carcinoma

,

chronic urticaria

,

,

waldenstrom macroglobulinemia

,

peripheral nervous system diseases

,

,

,

,

,

peptic ulcer hemorrhage

,

,

allergic rhinitis

,

,

allergic rhinitis perennial

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

b-cell lymphoma

,

lymphoid leukemia

,

atherosclerosis

,

intracranial arteriosclerosis

,

fallopian tube neoplasms

,

colorectal neoplasms

,

head and neck neoplasms

,

healthy volunteers/patients

,

,

,

squamous cell carcinoma

,

hypersensitivity

,

non-small-cell lung carcinoma

,

triple negative breast neoplasms

,

ovarian epithelial carcinoma

,

renal cell carcinoma

,

,

peanut hypersensitivity

,

allergic rhinitis

,

,

basal cell carcinoma

,

squamous cell carcinoma of head and neck

,

merkel cell carcinoma

,

neoplasm metastasis

,

basal cell neoplasms

,

,

,

,

adenocarcinoma of lung

,

milk hypersensitivity

,

multiple myeloma

,

plasma cell neoplasms

,

smoldering multiple myeloma

,

paraproteinemias

,

monoclonal gammopathy of undetermined significance

,

prostatic neoplasms

,

ovarian neoplasms

,

retinal diseases

,

diabetic retinopathy

,

,

,

protein-losing enteropathies

,

intestinal diseases

,

myositis ossificans

,

vitreous hemorrhage

,

type 2 diabetes mellitus

,

hyperlipidemias

,

diabetes mellitus

,

macular degeneration

,

,

healthy volunteers/patients

,

diabetes mellitus

,

type 2 diabetes mellitus

,

,

type 1 diabetes mellitus

,

rheumatoid arthritis

,

,

pharmacokinetics

,

coronavirus infections

,

,

hematologic neoplasms

Polyglycolic acid

hypersensitivity

,

peanut hypersensitivity

,

,

retinal detachment

,

,

uveal neoplasms

,

dissociative disorders

,

,

,

biliary liver cirrhosis

,

,

pancreatic neoplasms

,

,

periodontal pocket

,

,

gingival recession

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

,

,

pancreatic fistula

,

,

gastrointestinal diseases

,

digestive system diseases

,

,

surgical anastomosis

,

knee osteoarthritis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

communicable diseases

,

wounds and injuries

,

postoperative pain

,

drug-related side effects and adverse reactions

,

,

,

,

,

spinal cord injuries

,

spinal injuries

,

thyroid neoplasms

,

thyroid diseases

,

,

alveolar bone loss

,

wound infection

,

surgical wound infection

,

,

limbal stem cell deficiency

,

,

cartilage diseases

,

dental implants

,

edentulous jaw partially

,

alveolar ridge augmentation

,

,

edentulous mouth

,

cesarean section

,

pituitary neoplasms

,

cerebrospinal fluid leak

,

pituitary diseases

,

,

mycobacterium avium complex

,

,

mycobacterium avium-intracellulare infection

,

mycobacterium infections

Globulin, immune

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

mantle-cell lymphoma

,

small cell lung carcinoma

,

renal cell carcinoma

,

kidney neoplasms

,

,

,

,

follicular lymphoma

,

myelodysplastic syndromes

,

thrombocytopenia

,

aplastic anemia

,

,

,

bone marrow failure disorders

,

,

electrocardiography

,

,

hepatic insufficiency

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

multiple myeloma

,

plasma cell neoplasms

,

non-small-cell lung carcinoma

,

non-hodgkin lymphoma

,

neoplasm metastasis

,

colonic neoplasms

,

rectal neoplasms

,

,

,

triple negative breast neoplasms

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia

,

myeloid leukemia accelerated phase

,

,

philadelphia chromosome

,

,

cystadenocarcinoma

,

carcinoid tumor

,

ductal carcinoma breast

,

hemangiosarcoma

,

,

fracture healing

,

,

post-traumatic headache

,

,

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

kidney transplantation

,

graft rejection

,

kidney diseases

,

iga glomerulonephritis

,

,

invasive hydatidiform mole

,

,

breast neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

stomach neoplasms

,

,

thyroid diseases

,

,

,

homozygous familial hypercholesterolemia

,

human influenza

,

atopic dermatitis

,

,

,

immunoglobulin g4-related disease

,

colorectal neoplasms

,

hyperlipidemias

,

,

hypercholesterolemia

,

,

graves ophthalmopathy

,

,

rheumatoid arthritis

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

giant cell tumor of bone

,

giant cell tumors

,

hyperlipoproteinemias

,

hyperlipoproteinemia type ii

,

neuromyelitis optica

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

coronary artery disease

,

myocardial ischemia

,

atherosclerosis

renal cell carcinoma

,

,

non-small-cell lung carcinoma

,

endometrial neoplasms

,

hepatocellular carcinoma

,

stomach neoplasms

,

,

liver neoplasms

,

,

gastrointestinal neoplasms

,

female genital neoplasms

,

neuroendocrine tumors

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

breast neoplasms

myelodysplastic syndromes

,

thoracic neoplasms

,

glandular and epithelial neoplasms

,

,

,

pharmacokinetics

,

soft tissue neoplasms

,

digestive system neoplasms

,

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

endocrine gland neoplasms

,

breast diseases

,

bronchial neoplasms

,

intraductal carcinoma noninfiltrating

,

,

oligodendroglioma

,

,

pancreatic neoplasms

,

neoplasm metastasis

,

,

b-cell lymphoma

,

brain neoplasms

,

large b-cell lymphoma diffuse

,

castration-resistant prostatic neoplasms

,

non-hodgkin lymphoma

,

t-cell lymphoma

,

,

cholangiocarcinoma

,

myeloid leukemia acute

,

neuroendocrine tumors

,

follicular lymphoma

,

neuroendocrine carcinoma

,

t-cell lymphoma peripheral

,

kidney neoplasms

,

thyroid neoplasms

,

pancreatic ductal carcinoma

,

uterine neoplasms

,

uveal neoplasms

,

myeloid leukemia

,

invasive hydatidiform mole

,

lymphoid leukemia

,

,

female genital neoplasms

,

small cell carcinoma

,

urethral neoplasms

,

colonic neoplasms

,

vulvar neoplasms

,

b-cell lymphoma marginal zone

,

,

thyroid diseases

,

cutaneous malignant melanoma

,

,

microsatellite repeats

,

gastrointestinal neoplasms

,

mouth neoplasms

,

oropharyngeal neoplasms

,

laryngeal neoplasms

,

ureteral neoplasms

,

salivary gland neoplasms

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

penile neoplasms

,

b-cell chronic lymphocytic leukemia

,

hemangiosarcoma

,

,

,

mullerian mixed tumor

,

,

thymus neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

rectal neoplasms

,

hypopharyngeal neoplasms

,

male genital neoplasms

,

bile duct neoplasms

,

respiratory tract infections

,

papillomavirus infections

,

,

adenoid cystic carcinoma

,

,

male breast neoplasms

,

,

malignant fibrous histiocytoma

,

epstein-barr virus infections

,

adenocarcinoma of lung

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

,

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

,

pelvic neoplasms

,

,

germ cell and embryonal neoplasms

,

neoplasms by histologic type

,

adenoviridae infections

,

basal cell carcinoma

,

anaplastic thyroid carcinoma

,

reactive arthritis

,

gallbladder neoplasms

,

clear cell adenocarcinoma

,

adenosquamous carcinoma

,

gestational trophoblastic disease

,

alveolar soft part sarcoma

,

biphenotypic leukemia acute

,

local neoplasm recurrence

,

,

,

meningeal carcinomatosis

,

papillomaviridae

,

second primary neoplasms

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

intestinal diseases

,

,

carcinoma in situ

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

squamous intraepithelial lesions of the cervix

,

central nervous system diseases

,

extranodal nk-t-cell lymphoma

,

,

,

,

unknown primary neoplasms

,

synovial sarcoma

,

,

oral leukoplakia

,

,

lymphoproliferative disorders

,

,

colonic diseases

,

histiocytic sarcoma

,

follicular dendritic cell sarcoma

,

interdigitating dendritic cell sarcoma

,

environmental biomarkers

,

circulating neoplastic cells

,

inflammatory breast neoplasms

,

meningeal neoplasms

,

intestinal neoplasms

,

central nervous system neoplasms

,

nervous system neoplasms

,

nervous system diseases

,

nerve tissue neoplasms

,

primitive neuroectodermal tumors

,

neuroepithelial neoplasms

,

neuroectodermal tumors

,

adrenocortical carcinoma

,

carcinoid tumor

,

mediastinal neoplasms

,

testicular neoplasms

,

gastrointestinal stromal tumors

,

hairy cell leukemia

,

burkitt lymphoma

,

laryngeal diseases

,

vaginal neoplasms

,

acinar cell carcinoma

,

adenomyoepithelioma

,

hereditary breast and ovarian cancer syndrome

,

maxillary sinus neoplasms

,

basal cell neoplasms

,

urogenital neoplasms

,

male urogenital diseases

,

urogenital diseases

,

,

,

breast neoplasms

,

colorectal neoplasms

,

triple negative breast neoplasms

,

,

renal cell carcinoma

,

,

ovarian neoplasms

,

,

head and neck neoplasms

,

urinary bladder neoplasms

,

prostatic neoplasms

,

esophageal neoplasms

,

stomach neoplasms

,

liver neoplasms

,

hepatocellular carcinoma

,

endometrial neoplasms

,

uterine cervical neoplasms

,

ovarian epithelial carcinoma

,

small cell lung carcinoma

,

transitional cell carcinoma

,

hodgkin disease

,

fallopian tube neoplasms

,

urologic neoplasms

,

multiple myeloma

,

,

squamous cell neoplasms

,

,

plasma cell neoplasms

,

,

biliary tract neoplasms

,

esophageal squamous cell carcinoma

,

malignant mesothelioma

,

peritoneal neoplasms

,

microsatellite instability

,

merkel cell carcinoma

,

non-muscle invasive bladder neoplasms

,

hematologic neoplasms

,

hypersensitivity

,

nasopharyngeal neoplasms

,

disease progression

,

nasopharyngeal carcinoma

,

muscle neoplasms

,

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

healthy volunteers/patients

Antineoplaston a10

,

posterior uveitis

,

,

,

ocular hypertension

,

open-angle glaucoma

healthy volunteers/patients

1

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