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Loxo Oncology
Loxo Oncology
(LOXO)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Jaypirca
Pirtobrutinib
2023-01-27
2036
Mantle-cell lymphoma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Pirtobrutinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
preleukemia
,
syndrome
,
multiple myeloma
,
burkitt lymphoma
,
renal insufficiency
,
liver failure
,
hepatic insufficiency
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
large b-cell lymphoma diffuse
,
follicular lymphoma
,
interdigitating dendritic cell sarcoma
,
neoplasms
,
hairy cell leukemia
,
hematologic neoplasms
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
thrombocytopenic purpura idiopathic
,
central nervous system neoplasms
,
mantle-cell lymphoma
,
lymphoma
,
lymphoid leukemia
,
b-cell lymphoma
,
leukemia
,
hematologic diseases
,
reactive arthritis
,
b-cell leukemia
,
recurrence
,
b-cell chronic lymphocytic leukemia
,
non-hodgkin lymphoma
,
atrial fibrillation
,
sudden death cardiac
,
heart arrest
,
supraventricular tachycardia
Benzodiazepine
healthy volunteers/patients
,
psoriatic arthritis
,
psoriasis
,
cystic fibrosis
Dabigatran
healthy volunteers/patients
,
overweight
,
covid-19
,
atopic dermatitis
,
atrial fibrillation
,
hemorrhage
,
stroke
,
embolism
,
venous thromboembolism
,
neoplasms
,
thrombosis
,
thromboembolism
Benzimidazole
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
healthy volunteers/patients
,
stomach diseases
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
b-cell lymphoma
,
hypertension
Menatetrenone
embolism
,
healthy volunteers/patients
,
venous thrombosis
,
venous thromboembolism
,
thrombosis
,
stroke
,
rheumatic heart disease
,
transient ischemic attack
,
thromboembolism
,
atrial fibrillation
,
pulmonary embolism
,
ischemic stroke
,
intracranial hemorrhages
,
acute coronary syndrome
,
gastrointestinal hemorrhage
,
renal insufficiency
Tirabrutinib
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
mantle-cell lymphoma
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
interdigitating dendritic cell sarcoma
Aspartame
gastrointestinal stromal tumors
,
anemia
,
iron-deficiency anemia
,
iron deficiencies
,
glioblastoma
,
gliosarcoma
,
lung neoplasms
,
small cell lung carcinoma
,
healthy volunteers/patients
,
disease
,
leukemia
,
diarrhea
,
primary myelofibrosis
,
myeloid leukemia acute
,
myeloid leukemia
,
prostatic neoplasms
,
carcinoma
,
hepatocellular carcinoma
,
plexiform neurofibroma
,
neurofibromatoses
,
neurofibroma
,
thalassemia
,
iron overload
,
chronic obstructive pulmonary disease
,
obesity
,
overweight
,
triple negative breast neoplasms
,
pre-eclampsia
,
eclampsia
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
lupus nephritis
,
inflammatory breast neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
hemorrhage
,
wiskott-aldrich syndrome
,
bcr-abl positive chronic myelogenous leukemia
,
metaplasia
,
hematopoietic stem cell transplantation
,
bronchiolitis obliterans syndrome
,
syndrome
,
hyperlipoproteinemia type ii
,
graft vs host disease
,
organ transplantation
,
homozygous familial hypercholesterolemia
,
cryopyrin-associated periodic syndromes
,
motor activity
,
psychology rejection
,
myelodysplastic syndromes
,
preleukemia
,
liver transplantation
,
thrombocytopenic purpura idiopathic
,
thrombocytopenic purpura
,
purpura
,
parkinson disease
,
dyskinesias
,
eosinophilia
,
cellulitis
,
juvenile arthritis
,
arthritis
,
hepatitis b
,
hepatitis b virus
,
macular edema
,
edema
,
pituitary acth hypersecretion
,
osteoporosis
,
acute coronary syndrome
,
stroke
,
myocardial infarction
,
coronary stenosis
,
atherosclerotic plaque
,
inflammation
,
bronchitis
,
hypersensitivity
,
pulmonary eosinophilia
,
pancreatic neoplasms
,
fistula
,
delirium
,
kidney transplantation
,
asthma
,
hypercholesterolemia
,
atherosclerosis
,
breast neoplasms
,
neoplasms
,
hyperlipidemias
,
cardiovascular diseases
,
chronic kidney failure
,
kidney diseases
,
thrombocytopenia
,
heart failure
,
infections
,
coronary artery disease
,
dyslipidemias
,
chagas disease
,
chronic renal insufficiency
,
renal dialysis
,
renal replacement therapy
,
renal insufficiency
,
drug-related side effects and adverse reactions
,
heart transplantation
,
polycystic kidney diseases
,
autosomal dominant polycystic kidney
,
arthrogryposis
,
cystic fibrosis
,
pseudomonas infections
,
type 2 diabetes mellitus
,
hypoglycemia
,
multiple myeloma
,
plasma cell neoplasms
,
transplantation
,
cytomegalovirus infections
,
communicable diseases
,
neoplasm metastasis
,
metabolic syndrome
,
preconception care
,
drug interactions
,
percutaneous coronary intervention
,
melanoma
,
schizophrenia
Bevifimod
phenylketonurias
Nadide
diabetic neuropathies
,
neuralgia
,
postherpetic neuralgia
Retinol
melanoma
,
carcinoma
,
neoplasms
,
non-small-cell lung carcinoma
,
head and neck neoplasms
,
lung neoplasms
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
adenocarcinoma
,
bronchial diseases
,
neoplasms by histologic type
,
neoplasms by site
,
nerve tissue neoplasms
,
osteoporosis
,
postmenopausal osteoporosis
,
chronic renal insufficiency
,
vitamin d deficiency
,
renal insufficiency
,
kidney transplantation
,
anemia
Globulin, immune
prostatic neoplasms
,
small cell carcinoma
,
neuroendocrine tumors
Digitalis
healthy volunteers/patients
,
rheumatoid arthritis
,
arthritis
,
type 2 diabetes mellitus
,
drug interactions
Endocrine
castration-resistant prostatic neoplasms
,
non-small-cell lung carcinoma
,
healthy volunteers/patients
,
ovarian neoplasms
,
triple negative breast neoplasms
,
liposarcoma
,
colorectal neoplasms
,
adenocarcinoma of lung
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
neoplasms
,
prostatic neoplasms
,
recurrence
,
type 2 diabetes mellitus
,
male breast neoplasms
,
endocrine system diseases
,
diabetes mellitus
,
unilateral breast neoplasms
,
neoplasm metastasis
,
obesity
,
glucose metabolism disorders
,
metabolic diseases
,
body weight
,
overweight
,
nutrition disorders
,
signs and symptoms
,
nutritional and metabolic diseases
,
signs and symptoms pathological conditions
,
overnutrition
,
breast neoplasms
,
acromegaly
,
left ventricular hypertrophy
,
left ventricular dysfunction
,
laron syndrome
,
pituitary dwarfism
,
bipolar disorder
,
coronary disease
,
coronary artery disease
Lactams
healthy volunteers/patients
,
meningitis
,
non-hodgkin lymphoma
,
multiple myeloma
,
bacterial infections
,
fever
,
pulmonary tuberculosis
,
multidrug-resistant tuberculosis
,
infections
,
communicable diseases
,
appendicitis
,
peritonitis
,
bacterial pneumonia
,
abdominal abscess
,
ileus
,
pyelonephritis
,
pancreatitis
,
cholecystitis
,
bacterial infections and mycoses
,
chronic bronchitis
,
bronchitis
,
acute disease
,
respiratory tract diseases
,
lung diseases
,
otitis media
,
otitis
,
cross infection
,
community-acquired infections
,
abdominal pain
,
abscess
,
intestinal perforation
,
acute abdomen
,
rupture
,
mechanical ventilators
,
pneumonia
,
ventilator-associated pneumonia
,
healthcare-associated pneumonia
,
urinary tract infections
,
intraabdominal infections
,
sepsis
,
wounds and injuries
,
retinal detachment
,
dissociative disorders
Mk3475
squamous cell carcinoma of head and neck
,
melanoma
,
recurrence
,
triple negative breast neoplasms
,
renal cell carcinoma
,
neoplasms
,
urologic neoplasms
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
colorectal neoplasms
,
prostatic neoplasms
,
non-small-cell lung carcinoma
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
lung neoplasms
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