Loxo Oncology - PharmaKB

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Disease Reports

Company ReportsLoxo Oncology

Loxo Oncology(LOXO)

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Therapeutic Areas:

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Jaypirca	Pirtobrutinib	2023-01-27	2036	Mantle-cell lymphoma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

healthy volunteers/patients

,

prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

,

atrial fibrillation

,

venous thromboembolism

,

ischemic stroke

,

thromboembolism

,

,

sickle cell anemia

allergic rhinitis seasonal

,

nasal obstruction

,

,

,

restless legs syndrome

,

spinal cord injuries

,

type 1 diabetes mellitus

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

,

neurologic manifestations

,

wounds and injuries

,

central nervous system diseases

,

spinal cord diseases

,

sleep wake disorders

,

inguinal hernia

,

peripheral nervous system diseases

,

,

,

,

healthy volunteers/patients

,

,

partial epilepsies

,

diabetic neuropathies

,

,

,

sleep initiation and maintenance disorders

,

,

postherpetic neuralgia

,

postoperative pain

,

anxiety disorders

,

,

generalized anxiety disorder

,

complex partial epilepsy

,

,

,

bronchiolitis obliterans syndrome

,

,

,

intractable pain

,

,

,

renal insufficiency

,

pharmacovigilance

postoperative nausea and vomiting

,

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

,

colonic neoplasms

,

,

rectal neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

,

chronic hepatitis c

,

,

,

esophageal squamous cell carcinoma

,

hypercholesterolemia

,

Globulin, immune

rectal neoplasms

,

ovarian epithelial carcinoma

,

b-cell lymphoma marginal zone

,

hematologic diseases

,

myeloid leukemia

,

laryngeal diseases

,

,

liver neoplasms

,

alveolar soft part sarcoma

,

,

healthy volunteers/patients

,

,

,

,

,

malignant mesothelioma

,

,

microsatellite instability

,

,

thymus neoplasms

,

cutaneous malignant melanoma

,

,

central nervous system neoplasms

,

biphenotypic leukemia acute

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

colonic neoplasms

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

colorectal neoplasms

,

renal cell carcinoma

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

alzheimer disease

,

head and neck neoplasms

,

b-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

squamous cell carcinoma

,

kidney neoplasms

,

,

,

large b-cell lymphoma diffuse

,

prostatic neoplasms

,

,

pancreatic neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

,

sickle cell anemia

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

castration-resistant prostatic neoplasms

,

ovarian neoplasms

,

intestinal diseases

,

mantle-cell lymphoma

,

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

bone marrow diseases

,

hypercholesterolemia

,

hepatocellular carcinoma

,

allergic rhinitis

,

,

,

invasive hydatidiform mole

,

stomach neoplasms

,

streptococcal infections

,

inflammatory bowel diseases

,

human influenza

,

,

waldenstrom macroglobulinemia

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

margins of excision

,

hereditary sensory and autonomic neuropathies

,

,

cardiovascular diseases

,

type 2 diabetes mellitus

,

atherosclerosis

,

hyperlipoproteinemia type ii

,

,

pancreatic ductal carcinoma

,

membranous glomerulonephritis

,

small cell lung carcinoma

,

neuroendocrine tumors

,

mucocutaneous lymph node syndrome

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

hidradenitis suppurativa

,

,

anaplastic thyroid carcinoma

,

communicable diseases

,

bacterial infections

,

gram-positive bacterial infections

,

,

smoldering multiple myeloma

,

second primary neoplasms

,

,

japanese encephalitis

,

,

myelomonocytic leukemia acute

,

central serous chorioretinopathy

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

squamous cell neoplasms

,

hodgkin disease

,

neuroendocrine carcinoma

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

fallopian tube neoplasms

,

coronavirus infections

,

,

,

eosinophilic esophagitis

,

,

female infertility

,

solar urticaria

,

angioid streaks

,

pseudoxanthoma elasticum

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

diffuse scleroderma

,

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

,

non-small-cell lung carcinoma

,

,

,

,

multiple sclerosis

,

,

,

,

meningococcal meningitis

,

cryopyrin-associated periodic syndromes

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

iga glomerulonephritis

,

non-hodgkin lymphoma

,

,

,

,

follicular lymphoma

,

brain neoplasms

,

paroxysmal hemoglobinuria

,

,

retinopathy of prematurity

,

giant cell arteritis

,

polymyalgia rheumatica

,

graft rejection

,

aplastic anemia

,

,

,

,

juvenile arthritis

,

haemophilus infections

,

degenerative myopia

,

ankylosing spondylitis

,

graft vs host disease

,

psychology rejection

,

organ transplantation

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

gouty arthritis

,

osteitis deformans

,

,

,

allergic rhinitis seasonal

,

hematologic neoplasms

,

,

neovascular glaucoma

,

,

neoplasms by site

,

thrombocytopenic purpura idiopathic

,

chronic obstructive pulmonary disease

,

,

,

,

familial mediterranean fever

,

,

peanut hypersensitivity

,

axial spondyloarthritis

,

,

,

,

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

choroid diseases

,

uveal neoplasms

,

,

,

,

pulmonary eosinophilia

,

,

,

alpha 1-antitrypsin deficiency

,

lupus nephritis

,

,

glomerulonephritis

,

urologic diseases

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

breast neoplasms

,

macular degeneration

,

,

,

,

,

choroidal neovascularization

,

vision disorders

,

kidney transplantation

,

meningococcal infections

,

retinal vein occlusion

,

rheumatoid arthritis

,

neoplasm metastasis

,

chronic urticaria

,

psoriatic arthritis

,

diabetic retinopathy

,

,

liver transplantation

,

kidney diseases

,

relapsing-remitting multiple sclerosis

,

diabetes mellitus

,

spondylarthritis

,

retinal diseases

,

,

renal insufficiency

,

wet macular degeneration

,

geographic atrophy

,

pathologic neovascularization

,

,

polypoidal choroidal vasculopathy

,

hypersensitivity

,

chronic renal insufficiency

,

chronic kidney failure

,

thrombocytopenia

,

,

retinal neovascularization

,

retinal detachment

,

diabetes complications

,

migraine disorders

,

,

,

food hypersensitivity

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

,

tick-borne encephalitis

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

,

liver cirrhosis

,

,

,

reperfusion injury

,

delayed graft function

,

,

,

hematopoietic stem cell transplantation

,

chronic progressive multiple sclerosis

atrial fibrillation

,

cardiac arrhythmias

renal cell carcinoma

,

,

non-small-cell lung carcinoma

,

urinary bladder neoplasms

,

,

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