Loxo Oncology - PharmaKB

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Disease Reports

Company ReportsLoxo Oncology

Loxo Oncology(LOXO)

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Therapeutic Areas:

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Jaypirca	Pirtobrutinib	2023-01-27	2036	Mantle-cell lymphoma

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

atopic dermatitis

,

,

,

type 2 diabetes mellitus

,

healthy volunteers/patients

,

,

pulmonary tuberculosis

,

,

diabetes mellitus

,

insulin resistance

drug interactions

thromboembolism

,

venous thromboembolism

,

pulmonary embolism

healthy volunteers/patients

,

alzheimer disease

,

female genital neoplasms

,

,

chronic hepatitis b

,

,

major depressive disorder

,

depressive disorder

,

triple negative breast neoplasms

,

pancreatic neoplasms

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

sickle cell anemia

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

parkinson disease

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

chronic hepatitis

,

rectal neoplasms

,

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

antiphospholipid syndrome

,

respiratory insufficiency

,

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

lupus nephritis

,

human influenza

,

breast neoplasms

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

myeloid leukemia acute

,

multiple sclerosis

,

,

hepatocellular carcinoma

,

colonic neoplasms

,

thrombocytopenic purpura idiopathic

,

liver cirrhosis

,

neuromyelitis optica

,

membranous glomerulonephritis

,

chronic progressive multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

nephrotic syndrome

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

hemolytic anemia autoimmune

,

,

chronic hepatitis c

,

,

,

rheumatoid arthritis

,

,

,

juvenile arthritis

,

,

follicular lymphoma

,

,

,

myelodysplastic syndromes

,

,

,

acquired immunodeficiency syndrome

,

kidney transplantation

,

drug-related side effects and adverse reactions

,

heart disease risk factors

,

cognitive dysfunction

hematologic neoplasms

,

biphenotypic leukemia acute

,

b-cell leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

myelodysplastic syndromes

,

,

muscle spasticity

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

b-cell lymphoma

,

ovarian neoplasms

,

,

b-cell lymphoma marginal zone

,

fallopian tube neoplasms

,

burkitt lymphoma

,

multiple myeloma

,

prostatic neoplasms

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

esophageal neoplasms

,

squamous cell carcinoma of head and neck

,

reactive arthritis

,

waldenstrom macroglobulinemia

,

lymphoproliferative disorders

,

lymphatic diseases

,

intestinal neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

,

,

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

,

primary myelofibrosis

,

,

hairy cell leukemia

,

abdominal hernia

,

,

breast neoplasms

,

urinary bladder neoplasms

,

uterine neoplasms

,

knee osteoarthritis

,

residual neoplasm

,

,

interstitial cystitis

,

neoadjuvant therapy

,

ovarian epithelial carcinoma

,

mantle-cell lymphoma

,

female genital neoplasms

,

peritoneal neoplasms

,

,

non-hodgkin lymphoma

,

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

,

myeloid leukemia acute

,

colorectal neoplasms

,

large b-cell lymphoma diffuse

,

follicular lymphoma

,

,

,

musculoskeletal diseases

,

ankylosing spondylitis

,

small cell lung carcinoma

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

inflammatory bowel diseases

,

macular degeneration

,

,

juvenile arthritis

,

neoplasm metastasis

,

,

papulosquamous skin diseases

,

wet macular degeneration

,

,

lymphoid leukemia

,

,

communicable diseases

,

bacterial infections

,

methicillin-resistant staphylococcus aureus

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

disease progression

,

,

parkinson disease

,

bronchopulmonary dysplasia

,

respiratory syncytial viruses

,

,

,

pyoderma gangrenosum

,

spondylarthropathies

,

spondylarthritis

,

spinal diseases

,

,

intermediate uveitis

,

posterior uveitis

,

precocious puberty

,

migraine disorders

,

retinal diseases

,

retinal degeneration

,

,

choroidal neovascularization

,

hepatocellular carcinoma

,

liver neoplasms

,

thyroid diseases

,

,

rheumatoid arthritis

,

,

,

ulcerative colitis

,

psoriatic arthritis

,

,

chronic hepatitis c

,

hidradenitis suppurativa

,

axial spondyloarthritis

,

cardiovascular diseases

,

connective tissue diseases

,

,

,

,

drug monitoring

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

healthy volunteers/patients

knee osteoarthritis

,

Globulin, immune

renal cell carcinoma

,

uterine cervical neoplasms

,

,

hepatocellular carcinoma

,

esophageal squamous cell carcinoma

,

urologic neoplasms

,

liver neoplasms

,

basal cell carcinoma

,

,

transitional cell carcinoma

,

esophageal neoplasms

,

uveal neoplasms

,

,

digestive system neoplasms

,

ovarian epithelial carcinoma

,

hereditary breast and ovarian cancer syndrome

,

hereditary sensory and autonomic neuropathies

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

,

breast neoplasms

,

,

merkel cell carcinoma

,

,

small cell lung carcinoma

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

pancreatic neoplasms

,

squamous cell carcinoma

,

myeloproliferative disorders

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

triple negative breast neoplasms

,

hodgkin disease

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

primary myelofibrosis

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

endometrial neoplasms

,

stomach neoplasms

,

cholangiocarcinoma

,

ovarian neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

,

multiple myeloma

,

,

animal mammary neoplasms

,

,

burkitt lymphoma

,

philadelphia chromosome

,

epstein-barr virus infections

,

,

myelomonocytic leukemia acute

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myelomonocytic leukemia juvenile

,

prolymphocytic leukemia

,

refractory anemia with excess of blasts

,

b-cell leukemia

,

thrombocytopenic purpura idiopathic

,

b-cell lymphoma

,

non-small-cell lung carcinoma

,

colorectal neoplasms

,

large b-cell lymphoma diffuse

,

squamous cell carcinoma of head and neck

,

graft vs host disease

,

follicular lymphoma

,

,

,

bronchiolitis obliterans syndrome

,

b-cell lymphoma marginal zone

,

,

head and neck neoplasms

,

neoplasm metastasis

,

mantle-cell lymphoma

,

colonic neoplasms

,

rheumatoid arthritis

healthy volunteers/patients

renal cell carcinoma

,

,

non-small-cell lung carcinoma

,

endometrial neoplasms

,

hepatocellular carcinoma

,

stomach neoplasms

,

,

liver neoplasms

,

,

gastrointestinal neoplasms

,

neuroendocrine tumors

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

breast neoplasms

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